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The reigning AL Player of the Week, Verlander looks to stay hot against a familiar opponent in the White Sox. He is 20-13 with a 3.82 ERA in 42 starts vs. the South Siders but just 7-8 with a 4.11 ERA in 21 starts at Guaranteed Rate Field.
James Shields was scheduled to start Friday, but he pitched the 14th in Wednesday's loss to the A's. The White Sox will use their off-day to re-evaluate.
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The former Cy Young winner is still looking for his first victory as he enters his fifth start. He was a tough-luck loser last time out when he permitted just two runs over eight innings in a 2-1 loss to the Mariners in Seattle.
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Giolito will be working on eight days' rest after last pitching at Target Field on April 12. Giolito had greater success with his offspeed offerings against the Twins but was still bothered by somewhat spotty fastball command.
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McCullers tied his career high of 11 strikeouts while allowing only one hit (a first-inning homer) and one walk in seven innings Tuesday night in a victory over the Mariners. He has 34 strikeouts in 21 innings pitched this season.
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His record may not show it, due to a chronic lack of run support, but Lopez made a third straight quality start to open 2018 on Monday in Oakland, holding the A’s to two runs on four hits in six frames while fanning 10, one shy of his career-high.