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04/04/09 6:40 PM ET

Cain strikes out six, but Giants fall

Right-hander escapes early jam; Sandoval goes 2-for-3

at Oakland-Alameda County Coliseum
Saturday, April 4

Giants at the plate: Eugenio Velez's RBI groundout in the fifth inning erased Oakland's 1-0 lead, and Pablo Sandoval followed with his second hit of the game to break the tie.

A's at the plate: Ryan Sweeney singled to center field to open the bottom of the first inning, stole second base and eventually scored on a bases-loaded walk to Eric Chavez. Leading off the bottom of the sixth, Chavez homered for the second time in his past two games, and Jack Cust followed with his fourth spring homer to give Oakland a 3-2 lead.

Giants on the mound: Right-handed starter Matt Cain walked three in the first inning, including one with the bases loaded, but he also struck out the side and limited the damage to one run. Thereafter, Cain allowed one hit and one walk over three scoreless innings, and he finished with six strikeouts. Non-roster righty Ramon Ortiz gave up the home runs by Chavez and Cust.

A's on the mound: Rookie lefty Brett Anderson introduced himself to the home fans with a perfect first inning, capping it in style by striking out Sandoval. He didn't run into any real trouble until the fifth, when the Giants scored two runs on three hits. Anderson bounced back with a perfect sixth, and his final line was six hits and a walk with five strikeouts over 6 2/3 innings. Andrew Bailey took over for Anderson and didn't allow a run for the 11th time in 12 spring outings.

Up next: The Giants on Sunday will play their final exhibition game of the spring, hosting the Dodgers at 1:05 p.m. PT at AT&T Park. Lefty Jonathan Sanchez, San Francisco's No. 5 starter, will get the ball opposite Los Angeles righty James McDonald.

Mychael Urban is a national reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.