| 13-11 W-L | 3.14 ERA | 177 Ks |
| 2-0 W-L | 0.00 ERA | 13 Ks |
Only 26, Cain is one of the longest-tenured Giants, making his debut as a 20-year-old in 2005. Growing up as a kid in Alabama and Tennessee, Cain had never lived in a town with more than 3,000 people before being drafted.

05/21/2013: WSH@SF: Cain saves run with nice defensive play

05/21/2013: WSH@SF: Cain fans seven over seven strong innings

05/16/2013: SF@COL: Cain helps his cause with an RBI single

05/10/2013: ATL@SF: Cain drives in a run to extend Giants' lead

05/10/2013: Must C Cain: Cain hit by comebacker, gets the out

05/10/2013: ATL@SF: Cain twirls eight solid innings, Ks seven

05/10/2013: ATL@SF: Cain takes a hit, still gets out

05/07/2013: Jeremy Brisiel guides us through Darvish's dominance

05/05/2013: LAD@SF: Matt Cain on earning first win of 2013

05/05/2013: LAD@SF: Cain fans four through 7 1/3 frames